Why choose serological testing?

Q: Why consider serological allergy testing?

 

A: To give the option of providing the only management solution that can modify the natural course of a pre-existing hypersensitivity and result in the establishment of long-term clinical tolerance (1,2).

 

Q: Why choose serological testing over intradermal testing (IDT)?

 

A: Here are the top 5 reasons:

 

1. Minimal preparation / less invasive for patient.

2. Time efficient – quick and easy sample submission process.

3. Can be carried out while skin lesions are present.

4. Flexible – samples can be taken and stored when the patient is most symptomatic / off medication and then tested when required.

5. No difference in response rate to immunotherapy when compared to using intradermal testing (3,4).

 

References:

1. Griffin CE and Hillier A (2001). The ACVD task force on canine atopic dermatitis (XXIV): allergen-specific immunotherapy, Veterinary Immunology and Immunopathology;81(3-4): 363-383.

2. Fischer NM, Rostaher A and Favrot C (2019). Allergen-specificimmunotherapy in dogs with atopic dermatitis: a comparison of subcutaneous, intralymphatic and sublingual administration. In: Proceedings of the 31st Annual Congress of the European Society and College of Veterinary Dermatology, Liverpool, 2019.

3. Park S, Ohya F, Yamashita K, Nishifuji K, Iwasaki T. Comparison of response to immunotherapy by intradermal skin test and antigen-specific IgE in canine atopy. J Vet Med Sci. 2000 Sep;62(9):983-8. doi: 10.1292/jvms.62.983. PMID: 11039595.

4. Schnabl B, Bettenay SV, Dow K, Mueller RS. Results of allergen-specific immunotherapy in 117 dogs with atopic dermatitis. Vet Rec. 2006 Jan 21;158(3):81-5. doi: 10.1136/vr.158.3.81. PMID: 16428661.

 

 

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